The future of cities and regional development is fundamentally different from where we come from. In the article about “breaking with our heritage” I describe this breaking process at individual and city governance level. Nowadays it goes even further than breaking with the facilitating function of our industrial or capitalist economic heritage. This is necessary if we want to have a sustainable future as a human species. It therefore also breaks with hierarchical dominance, citizen domestication, money as prime goal, growth and our cultural behavioral (lack of) ethics, as we all, people and institutions alike, carry the same responsibility. It goes much further than the decorative transition suggested in this animated visualization (source: LinkedIn ). Many cities will have to redefine themselves and their economies, some will disappear or develop into smaller units.